| CARD ID | 871 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6;129-Wnk4tm1(D561A) | |
| Internal Code | Wnk4(D561A) knock-in mouse | |
| Submitter | - - | |
| Submitter affiliation or code | - | |
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
|
|
| Production method | in-house breeding | |
| Origin (In-house) | Organization | Tokyo Medical & Dental Univ. |
| Organization code | none | |
| Developer | Uchida Shinichi | |
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Wnk4 |
| Gene name | WNK lysine deficient protein kinase 4 |
| Allele symbol | |
| Allele name | |
| MGI | MGI:1917097, |
| Chromosome | 11 (syntenic) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| GO | Gene Ontology |
| OMIM | OMIM ID: 601844 Human Gene Symbol: WNK4, |
| SA-end-WNK4- | 5'-AGGCCTCGAACTCAGAGACTG-3' |
| LA1-1R-seg-WNK4- | 5'-TGCTGCACCAAGCATAAAGCA-3' |
| Author | Yang SS, Morimoto T, Rai T, Chiga M, Sohara E, Ohno M, Uchida K, Lin SH, Moriguchi T, Shibuya H, Kondo Y, Sasaki S, Uchida S. |
| Title | Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model. |
| Journal | Cell Metab. |
| Volume | 5 |
| Page | 331-44 |
| Year | 2007 |
| PMID |
| Disease name, Applicable field | Physiology, Metabolism |