| CARD ID | 681 | |
| Type of strain | Transgenic. | |
| Strain name | C57BL/6J-Tg(CMV-SMURF2)21 | |
| Internal Code | CMV -FLAG-Smurf2-Tg-line21,CMV-F-Smurf2(21) | |
| Submitter | Unknown Unknown | |
| Submitter affiliation or code | ||
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
|
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| Production method | in-house breeding | |
| Origin (In-house) | Organization | Dept. of Biochem., The JFCR Cancer Institute |
| Organization code | ||
| Developer | Takeshi IMAMURA | |
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | SMURF2 |
| Gene name | Smad ubiquitin reguratory factor2 |
| Allele symbol | |
| Allele name | |
| MGI | |
| Chromosome | Unknown , |
| Gene classification | Gene to express(transgenic) |
| Method | MicroInjection |
| OMIM | OMIM ID: 605532 Human Gene Symbol: SMURF2, |
| Tg-FLAG-SN | 5'-ATggACTACAAggACgATgATgACAAgg-3' |
| Tg-Smurf2-AS | 5'-gTTTAgATACTggATTCTTCCAgAggCg-3' |
| Author | Mitsuru Horiki, Takeshi Imamura, Mina Okamoto, Makoto Hayashi, Junko Murai, Akira Myoui, Takahiro Ochi, Kohei Miyazono, Hideki Yoshikawa, and Noriyuki Tsumaki |
| Title | Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia |
| Journal | Cell Biology |
| Volume | 165 |
| Page | 433-445 |
| Year | 2004 |
| PMID |
| Disease name, Applicable field | Development, cancer |