| CARD ID | 644 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6;CB-A4galttm1/Card | |
| Internal Code | Gb3KO | |
| Submitter | Koichi Furukawa | |
| Submitter affiliation or code | ||
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
|
|
| Production method | From other organizations | |
| Origin (In-house) | Organization | |
| Organization code | ||
| Developer | ||
| Origin (From other organizations) | Organization | Naoki Takeda |
| Organization code | Card | |
| Developer | Center for Animal Resources and Development | |
| Year introduced | 2003 / 4 | |
| Introduced Generation | F1 | |
| Remarks | ||
| Gene symbol | A4galt |
| Gene name | alpha 1,4-galactosyltransferase |
| Allele symbol | |
| Allele name | |
| MGI | |
| Chromosome | 15 (E2) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation, MicroInjection |
| OMIM |
| Neo-F1 | CGT GAT ATT GCT GAA GAG CTT GGC GGC GAA |
| 77KO-R1 | GAA CTC ATG CTT GCG CTC GAA GGC TAG GAA |
| Author | Tetsuya Okuda, Noriyo Tokuda, Shin-ichiro Numata, Masafumi Ito, Michio Ohta, Kumiko Kawamura, Joelle Wiels, Takeshi Urano, Orie Tajima, Keiko Furukawa, and Koichi Furukawa |
| Title | Targeted Disruption of Gb3/CD77 Synthase Gene Resulted in the Complete Deletion of Globo-series Glycosphingolipids and Loss of Sensitivity to Verotoxins |
| Journal | J. Biol. Chem. |
| Volume | 281 |
| Page | 10230-10235 |
| Year | 2006 |
| PMID |
| Disease name, Applicable field | Physiology, Development, Immunology, cancer, Metabolism |