| CARD ID | 527 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6.129-Kcnj8tm1Kusm | |
| Internal Code | Kir6.1 deficient mouse, B6.129-Kcnj8tm1Kusm | |
| Submitter | Unknown Unknown | |
| Submitter affiliation or code | ||
| Stock Type | ||
| Material Transfer Conditions |
Others
|
|
| Production method | in-house breeding | |
| Origin (In-house) | Organization | Div Cell & Mol Med, Kobe Univ Grad Sch Med |
| Organization code | Kusm | |
| Developer | Susumu Seino | |
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Kcnj8 (Synonym:Kir6.1) |
| Gene name | potassium inwardly-rectifying channel, subfamily J, member 8 |
| Allele symbol | Kcnj8tm1Kusm |
| Allele name | targeted mutation 1, Division of Cellular and Molecular Medicine, Kobe University School of Medicine |
| MGI | |
| Chromosome | 6 (70.0 cM) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| OMIM | OMIM ID: 600935 Human Gene Symbol: KCNJ8, |
| Kir6.1-KO-3fw | 5'-AAT GGC CGA TCC CAT ATT GG-3' |
| Kir6.1-KO-2rc | 5'-CTG AAC TGG TGA TGA GTG CA-3' |
| Author | TAKASHI MIKI, MASASHI SUZUKI, TADAO SHIBASAKI, HIROKO UEMURA, TOSHIAKI SATO, KAORI YAMAGUCHI, HARUHIKO KOSEKI, TOSHIHIKO IWANAGA, HARUAKI NAKAYA & SUSUMU SEINO |
| Title | Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1 |
| Journal | NATURE MEDICINE |
| Volume | 8 |
| Page | 466-472 |
| Year | 2002 |
| PMID | 11984590 |
| Disease name, Applicable field | Neurobiology, Physiology |