| CARD ID | 399 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6;129-Irf3tm1Isgf3gtm1 | |
| Internal Code | IRF-3 KO, IRF-9 KO, B6;129-Irf3tm1Isgf3gtm1 | |
| Submitter | Unknown Unknown | |
| Submitter affiliation or code | ||
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
|
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| Production method | in-house breeding | |
| Origin (In-house) | Organization | Department of Immunology, Graduate School of Medicine, The University of Tokyo |
| Organization code | ||
| Developer | Tadatsugu Taniguchi | |
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Irf3 |
| Gene name | interferon regulatory factor 3 |
| Allele symbol | Irf3tm1 |
| Allele name | Irf3, targeted mutation 1 |
| MGI | MGI:1859179, |
| Chromosome | 7 , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| GO | Gene Ontology |
| OMIM | OMIM ID: 603734 Human Gene Symbol: IRF3, |
| Gene symbol | Isgf3g (synonym:Irf-9) |
| Gene name | interferon dependent positive acting transcription factor 3 gamma |
| Allele symbol | Isgf3gtm1 |
| Allele name | Isgf3g, targeted mutation 1 |
| MGI | MGI:107587, |
| Chromosome | 14 , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| GO | Gene Ontology |
| OMIM | OMIM ID: 147574 Human Gene Symbol: IRF9, |
| primerA | IRF3 common: gaa cct cgg agt tat ccc gaa gg IRF3 d.s: gtt tga gtt atc cct gca ctt ggg Neo pri: tcg tgc ttt acg cta tcg ccg ctc ccg att ISGF3g: tca atg ttc cga tgt ggc agt tca aag gat c E3g: tat cga ata ctg cca gca gga acc c Neo p48: tc |
| primerB |
| Author | Tohru Kimura, Yuzo Kadokawa, Hisashi Harada, Masahito Matsumoto, Mitsuharu Sato, Yasuo Kashiwazaki, Masahito Tarutani, Rosemary Sok-Pin Tan, Tomohiro Takasugi, Toshifumi Matsuyama, Tak W. Mak, Shigeru Noguchi and Tadatsugu Taniguchi |
| Title | Essential and non-redundant roles of p48 (ISGF3γ)and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies |
| Journal | Genes to Cells |
| Volume | 1 |
| Page | 115-124 |
| Year | 1996 |
| PMID | 9078371 |
| Author | Mitsuharu Sato, Hirofumi Suemori, Naoki Hata, Masataka Asagiri, Kouetsu Ogasawara, Kazuki Nakao, Takeo Nakaya, Motoya Katsuki, Shigeru Noguchi, Nobuyuki Tanaka, and Tadatsugu Taniguchi |
| Title | Distinct and Essential Roles of Transcription Factors IRF-3 and IRF-7 in Response to Viruses for IFN-α/β Gene Induction |
| Journal | Immunity |
| Volume | 13 |
| Page | 539-548 |
| Year | 2000 |
| PMID | 11070172 |
| Disease name, Applicable field | Immunology |