CARD R-BASE



Mouse strain


Strain information

CARD ID 3180
Type of strain Transgenic., Targeted mutant.
Strain name B6D2-Nicol1em1OsbTg(CAG-Nicol1/PA/1D4)2Osb
Internal Code Gm1673 KO+ Tg
Submitter Ikawa Masahito
Submitter affiliation or code Animal Resource Center for Infectious Diseases Research Institute for Microbial Diseases Osaka University
Stock Type
Material Transfer Conditions Consent to us
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again.
Production method in-house breeding
Origin (In-house) Organization Department of Experimental Genome Research Research Institute for Microbial Diseases Osaka University
Organization code
Developer Masahito Ikawa, Kentaro Shimada
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Nicol1
Gene name NELL2 interacting cell ontogeny regulator 1
Allele symbol Tg(CAG-Nicol1/PA/1D4)2Osb
Allele name NELL2 interacting cell ontogeny regulator 1; transgene insertion 2, Research Institute for Microbial Diseases, Osaka University
MGI MGI:2686519,
Chromosome
Gene classification Gene to express(transgenic)
Method MicroInjection
OMIM
Gene symbol Nicol1
Gene name NELL2 interacting cell ontogeny regulator 1
Allele symbol Nicol1em1Osb
Allele name NELL2 interacting cell ontogeny regulator 1; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI MGI:2686519,
Chromosome
Gene classification Targeted or trapped gene(knockout etc.)
Method MicroInjection
OMIM



References

Author Kiyozumi D; Shimada K; Chalick M; Emori C; Kodani M; Oura S; Noda T; Endo T; Matzuk MM; Wreschner DH; Ikawa M
Title A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility.
Journal Nat Commun.
Volume 14 (1)
Page 2354
Year 2023
PMID 37095084


Disease , Applicable field information

Disease name, Applicable field






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