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CARD Mouse Bank

Mouse strain

Strain information

CARD ID 3062
Type of strain Targeted mutant.
Strain name B6D2-Tmem168em1(R539Q)Osb
Internal Code Tmem168 PM
Submitter Ikawa Masahito
Submitter affiliation or code Animal Resource Center for Infectious Diseases Research Institute for Microbial Diseases Osaka University
Stock Type
Material Transfer Conditions Consent to us
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again.
Production method in-house breeding
Origin (In-house) Organization
Organization code
Origin (From other organizations) Organization
Organization code
Year introduced
Introduced Generation

Gene information

Gene symbol Tmem168
Gene name transmembrane protein 168
Allele symbol Tmem168em1(R539Q)Osb
Allele name transmembrane protein 168; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University,
MGI MGI:1921794,
Gene classification Targeted or trapped gene(knockout etc.)
Method MicroInjection


Author Akio Shimizu Dimitar P. Zankov Akira Sato Masahiro Komeno Futoshi Toyoda Satoru Yamazaki Toshinori Makita Taichi Noda Masahito Ikawa Yoshihiro Asano Yohei Miyashita Seiji Takashima Hiroshi Morita Taisuke Ishikawa Naomasa Makita Masahito Hitosugi Hiroshi Matsuura Seiko Ohno Minoru Horie Hisakazu Ogita
Title Identification of transmembrane protein 168 mutation in familial Brugada syndrome
Journal FASEB J.
Volume 34(5)
Page 6399-6417
Year 2020

Disease , Applicable field information

Disease name, Applicable field

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