| CARD ID | 3034 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6D2-Pdha2em1Osb | |
| Internal Code | Pdha2 KO | |
| Submitter | Ikawa Masahito | |
| Submitter affiliation or code | Animal Resource Center for Infectious Diseases Research Institute for Microbial Diseases Osaka University | |
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again. |
|
| Production method | in-house breeding | |
| Origin (In-house) | Organization | |
| Organization code | ||
| Developer | ||
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Pdha2 |
| Gene name | pyruvate dehydrogenase E1 alpha 2 |
| Allele symbol | Pdha2em1Osb |
| Allele name | pyruvate dehydrogenase E1 alpha 2; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University |
| MGI | MGI:97533, |
| Chromosome | |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| OMIM |
| Author | Chen Pan, Keisuke Shimada , Hsin-Yi Chang, Haoting Wang, Masahito Ikawa |
| Title | Compensation for X-linked Pdha1 silencing by Pdha2 is essential for meiotic double-strand break repair in spermatogenesis |
| Journal | Development . |
| Volume | |
| Page | |
| Year | 2025 |
| PMID | 40679056 |
| Disease name, Applicable field |