| CARD ID | 2665 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6-Mir142em6Card | |
| Internal Code | miR142-30-8 | |
| Submitter | Masatake ARAKI | |
| Submitter affiliation or code | Gene Technology Center, IRDA, Kumamoto University | |
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
|
|
| Production method | in-house breeding | |
| Origin (In-house) | Organization | IRDA, Kumamoto University |
| Organization code | Card | |
| Developer | Masatake Araki | |
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Mir142 |
| Gene name | microRNA 142 |
| Allele symbol | |
| Allele name | |
| MGI | MGI:2676827, |
| Chromosome | |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| OMIM |
| mutS | 5'-TAA,CAG,CACTGGAGGGTGTG-3' |
| miR142-AS | 5'-TGA,GAG,ATG,CTC,ACC,TGT,TTC-3' |
| Author | Kawano, S. et al. |
| Title | A gain-of-function mutation in microRNA 142 is sufficient to cause the development of T-cell leukemia in mice. |
| Journal | Cancer Science |
| Volume | 114(7) |
| Page | 2821-2834 |
| Year | 2023 |
| PMID | 36945113 |
| Disease name, Applicable field | Immunology, Laboratory-animal Science, Development, Molecular biology |