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CARD Mouse Bank

Mouse strain

Strain information

CARD ID 2435
Type of strain Targeted mutant.
Strain name B6D2-Spink8em1Osb Spink8em2Osb
Internal Code Spink8 KO (+1/-5)
Submitter Ikawa Masahito
Submitter affiliation or code Animal Resource Center for Infectious Diseases Research Institute for Microbial Diseases Osaka University
Stock Type
Material Transfer Conditions Others
Production method
Origin (In-house) Organization
Organization code
Origin (From other organizations) Organization
Organization code
Year introduced
Introduced Generation

Gene information

Gene symbol Spink8
Gene name serine peptidase inhibitor, Kazal type 8
Allele symbol Spink8em1Osb Spink8em2Osb
Allele name serine peptidase inhibitor, Kazal type 8, endonuclease-mediated mutation 1,2, Research Institute for Microbial Diseases, Osaka University
MGI MGI:1925959,
Gene classification Targeted or trapped gene(knockout etc.)


Author Miyata H, Castaneda JM, Fujihara Y, Yu Z, Archambeault DR, Isotani A, Kiyozumi D, Kriseman ML, Mashiko D, Matsumura T, Matzuk RM, Mori M, Noda T, Oji A, Okabe M, Prunskaite-Hyyrylainen R, Ramirez-Solis R, Satouh Y, Zhang Q, Ikawa M, Matzuk MM.
Title Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice.
Journal Proc Natl Acad Sci U S A.
Volume 113(28)
Page 7704-10
Year 2016
PMID 27357688

Disease , Applicable field information

Disease name, Applicable field



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