| CARD ID | 2270 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6;129-DSCR-1tm1ApoEtm1 | |
| Internal Code | DSCR-1, ApoE double knockout mouse | |
| Submitter | Minami Takashi | |
| Submitter affiliation or code | Labs for Vascular Biology RCAST, The University of Tokyo | |
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
|
|
| Production method | in-house breeding | |
| Origin (In-house) | Organization | RCAST, The Univ. of Tokyo |
| Organization code | RAC10113 | |
| Developer | Takashi Minami | |
| Origin (From other organizations) | Organization | Harvard Univ. Medical School |
| Organization code | 不明 | |
| Developer | Juda Folkman, Sandra Ryeom | |
| Year introduced | 2008 / 6 | |
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | RCAN1 |
| Gene name | regulator of calcineurin 1 |
| Allele symbol | RCAN1tm1 |
| Allele name | regulator of calcineurin 1, targeted mutation 1, |
| MGI | MGI:1890564, |
| Chromosome | 16 (53.60) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| OMIM |
| Gene symbol | Apoe |
| Gene name | apolipoprotein E |
| Allele symbol | Apoetm1 |
| Allele name | apolipoprotein E, targeted mutation 1, |
| MGI | MGI:88057, |
| Chromosome | 7 (9.94) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | |
| OMIM |
| Author | Sandra Ryeom, Kwan-Hyuck Baek, Matthew J. Rioth, Ryan C. Lynch, Alexander Zaslavsky, Amy Birsner, Sam S. Yoon, and Frank McKeon |
| Title | Targeted Deletion of the Calcineurin Inhibitor DSCR1 Suppresses Tumor Growth |
| Journal | Cancer Cell |
| Volume | 13 |
| Page | 420-431 |
| Year | 2008 |
| PMID |
| Disease name, Applicable field | Physiology, Anatomy, cancer, Metabolism |