| CARD ID | 2029 | |
| Type of strain | Transgenic. | |
| Strain name | C57BL/6-Tg(CD46)1Ts | |
| Internal Code | CD46Tg | |
| Submitter | Seya Tsukasa | |
| Submitter affiliation or code | Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University | |
| Stock Type | ||
| Material Transfer Conditions |
Others
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| Production method | in-house breeding | |
| Origin (In-house) | Organization | Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaidou University |
| Organization code | ||
| Developer | Tsukasa Seya | |
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | CD46 |
| Gene name | CD46molecule, complement regulatory protein |
| Allele symbol | Tg(CD46)1Ts |
| Allele name | transgene insertion 1, Timothy Stewart |
| MGI | |
| Chromosome | Unknown , |
| Gene classification | Gene to express(transgenic) |
| Method | MicroInjection |
| OMIM |
| CD46-exon-se | gcc agt tca tct ttt gac tct att aa |
| CD46-exon-as | cag cat atc cct gct tta ata caa c |
| Author | Shingai M, Inoue N, Okuno T, Okabe M, Akazawa T, Miyamoto Y, Ayata M, Honda K, |
| Title | Wild-type measles virus infection in human CD46/CD150-transgenic mice: CD11c-positive dendritic cells establish systemic viral infection. |
| Journal | J Immunol. |
| Volume | 175(5) |
| Page | 3252-61 |
| Year | 2005 Sep 1 |
| PMID |
| Author | Miyagawa S, Mikata S, Tanaka H, Ikawa M, Kominami K, Seya T, Nishimune Y, Shirakura R, and Okabe M. |
| Title | The regulation of membrane cofactor protein (CD46) expression by the 3' untranslated region in transgenic mice. |
| Journal | Biochem. Biophys. Res. Commun. |
| Volume | 233 |
| Page | 829-833 |
| Year | 1997 |
| PMID |
| Author | Seya T, Hara T, Matsumoto M, and Akedo H. |
| Title | Quanatitative analysis of membrane cofactor protein (MCP) of complement: High expression of MCP on human leukemia cell lines, which is down-regulated during cell-differentiation. |
| Journal | J. Immunol. |
| Volume | 145 |
| Page | 238-245. |
| Year | 1990 |
| PMID |
| Disease name, Applicable field | Immunology |