| CARD ID | 1813 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6;129-Mll1tm1.1Mlc | |
| Internal Code | MlldC | |
| Submitter | Yokoyama Akihiko | |
| Submitter affiliation or code | Kyoto University Graduate School of Medicine Medical Innovation Center Laboratory for Malignancy Control Research DSK project | |
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
|
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| Production method | From other organizations | |
| Origin (In-house) | Organization | |
| Organization code | ||
| Developer | ||
| Origin (From other organizations) | Organization | Stanford University Medical School |
| Organization code | Mlc | |
| Developer | Michael L. Cleary | |
| Year introduced | 2009 / 5 | |
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Mll1 |
| Gene name | myeloid/lymphoid or mixed-lineage leukemia 1 |
| Allele symbol | Mll1tm1.1Mlc |
| Allele name | myeloid/lymphoid or mixed-lineage leukemia 1; targeted mutation 1.1, Michael L Cleary |
| MGI | MGI:96995, |
| Chromosome | 9 (24.84) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| OMIM |
| dC&uc.fwd | gttctgaagcacacattccacacc |
| dC&uc.rev | catcaaagcgaagggcaatcagtg |
| Author | Yokoyama, A., Ficara, F., Murphy, M. J., Meisel, C., Naresh, A., Kitabayashi, I. and Cleary, M. L. |
| Title | Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways. |
| Journal | J Cell Sci |
| Volume | 124 |
| Page | 2208-2219 |
| Year | 2011 |
| PMID |
| Disease name, Applicable field | Aging, Molecular biology, Cell biology, cancer, Endocrine Disorders, Hematology |