| CARD ID | 1585 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6;129-Tnnt2tm2Mmto | |
| Internal Code | B6;129-Tnnt2tm2Mmto | |
| Submitter | Morimoto Sachio | |
| Submitter affiliation or code | - | |
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
|
|
| Production method | in-house breeding | |
| Origin (In-house) | Organization | Kyushu University |
| Organization code | 不明 | |
| Developer | Sachio Morimoto | |
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Tnnt2 |
| Gene name | troponin T2, cardiac |
| Allele symbol | |
| Allele name | |
| MGI | MGI:104597, |
| Chromosome | 1 (60.0) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| OMIM | OMIM ID: 601494 Human Gene Symbol: CMD1D, |
| TNT F2 | 5'CCT AAG CCC CAG ACC TAT GC |
| TNT R2 | 5' GGT TCC TCC CCG TCC C |
| Author | Wang et al. |
| Title | Up-regulation of type 2 iodothyronine deiodinase in dilated cardiomyopathy. |
| Journal | Cardiovasc. Res. |
| Volume | 87(4) |
| Page | 636-646 |
| Year | 2010 |
| PMID |
| Author | Zhan et al. |
| Title | Therapeutic effect of {beta}-adrenoceptor blockers using a mouse model of dilated cardiomyopathy with a troponin mutation. |
| Journal | Cardiovasc. Res. |
| Volume | 84(1) |
| Page | 64-71 |
| Year | 2009 |
| PMID |
| Author | Sfichi-Duke et al. |
| Title | Cardiomyopathy-causing deletion K210 in cardiac troponin T alters phosphorylation propensity of sarcomeric proteins. |
| Journal | J. Mol. Cell. Cardiol. |
| Volume | 48(5) |
| Page | 934-942 |
| Year | 2010 |
| PMID |
| Author | Du et al. |
| Title | Knock-in mouse model of dilated cardiomyopathy caused by troponin mutation. |
| Journal | Circ. Res. |
| Volume | 101(2) |
| Page | 185-194 |
| Year | 2007 |
| PMID |
| Disease name, Applicable field | Physiology, Hematology |