| CARD ID | 1058 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6;129-Gtrgeo22tm1(Rosa26 Stop NICD2)99Imeg | |
| Internal Code | Rosa26 Stop NICD2 #99 | |
| Submitter | Nishinakamura Ryuichi | |
| Submitter affiliation or code | Department of Kidney Development, Institute of Molecular Embryology and Genetics Kumamoto University | |
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
|
|
| Production method | in-house breeding | |
| Origin (In-house) | Organization | Institute of Molecular Embryology and Genetics, Kumamoto University |
| Organization code | Imeg | |
| Developer | Ryuichi Nishinakamura | |
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | NICD2: intracellular domain of Notch2 | |
| Gene symbol | Gtrgeo22 |
| Gene name | gene trap ROSA b-geo 22 |
| Allele symbol | Gtrgeo22tm1(Rosa26 Stop NICD2)99Imeg |
| Allele name | targeted mutation 1, Institute of Molecular Embryology and Genetics |
| MGI | |
| Chromosome | 10 (43.0) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| OMIM |
| Neo | Forward:AAGGGACTGGCTGCTATTGG, Reverse: ATATCACGGGTAGCCAACGC |
| Rosa wild-type | Forward: GAGTTCTCTGCTGCCTCCTG, Reverse: CCGACAAAACCGAAAATCTG |
| Author | Fujimura S, Jiang Q, Kobayashi C, and Nishinakamura R |
| Title | Notch2 activation in the embryonic kidney depletes nephron progenitors |
| Journal | J. Am. Soc. Nephrol |
| Volume | 21(5) |
| Page | 803-810 |
| Year | 2010 |
| PMID |
| Disease name, Applicable field | Development |