CARD R-BASE



Mouse strain


Strain information

CARD ID 2034
Type of strain Targeted mutant.
Strain name C57BL/6-Hbegf tm1
Internal Code HBhz
Submitter Unknown Unknown
Submitter affiliation or code
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Osaka University, Research Institute for Microbial Diseases
Organization code
Developer Eisuke Mekada
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Hbegf
Gene name heparin-binding EGF-like growth factor
Allele symbol Hbegftm1
Allele name heparin-binding EGF-like growth factor, targeted mutation 1
MGI MGI:96070,
Chromosome 18 (19.46 ) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method
OMIM

PCR Primer 1
Intron3 Fw3 CAT GGG GTT GTG ACT CTC CT
Intron3 Rev3 AGC CTG CAC ACA CAA AAG TG
PCR Primer 2
GFP Fwd CAA GCA GAT CCT GAA GAA CA
GFP Rev GAA CAT CTC CTC GAT CAG GT


References

Author Tomoko Ichise1, Satoshi Adachi1, Minako Ohishi1, Masahito Ikawa2, Masaru Okabe2, Ryo Iwamoto1, and Eisuke Mekada
Title Humanized gene replacement in mice reveals the contribution of cancer stroma-derived HB-EGF to tumor growth
Journal
Volume
Page
Year
PMID


Disease , Applicable field information

Disease name, Applicable field






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