CARD R-BASE



Mouse strain


Strain information

CARD ID 708
Type of strain Transgenic.
Strain name B6;C3H-Tg(RIP-Ptgs2/RIP-Ptges)
Internal Code B6;C3H-Tg(RIP-Ptgs2/RIP-Ptges), RIP-C2mE
Submitter Masanobu Oshima
Submitter affiliation or code Division of Genetics, Cancer Research Institute, Kanazawa University
Stock Type
Material Transfer Conditions Others
Production method in-house breeding
Origin (In-house) Organization Cancer Research Institute, Kanazawa University
Organization code
Developer Hiroko Oshima
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Ptges (synonym:PmGES-1)
Gene name Ptges:prostaglandin E synthase
Allele symbol
Allele name
MGI MGI:1927593,
Chromosome
Gene classification Gene to express(transgenic)
Method MicroInjection
OMIM OMIM ID: 600262 Human Gene Symbol: PTGS2, OMIM ID: 605172 Human Gene Symbol: PTGES,
Gene symbol Ptgs2 (synonym:COX-2)
Gene name prostaglandin-endoperoxide synthase 2
Allele symbol
Allele name
MGI MGI:97798,
Chromosome
Gene classification Gene to express(transgenic)
Method MicroInjection
OMIM

PCR Primer 1
COX-2-F3 CAAACTCAAGTTTGACCCAG
COX-2-R1 CTTTTACAGCTCAGTTGAACG


References

Author Hiroko Oshima, Makoto Mark Taketo, and Masanobu Oshima
Title Destruction of Pancreatic β-Cells by Transgenic Induction of Prostaglandin E2 in the Islets
Journal J. Biol. Chem.
Volume 281
Page 29330-29336
Year 2006
PMID


Disease , Applicable field information

Disease name, Applicable field Unknown, Physiology, Metabolism






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