| CARD ID | 556 | |
| Type of strain | Targeted mutant. | |
| Strain name | ICR.129-Il6sttm1 | |
| Internal Code | gp130tm, ICR.129-Il6sttm1 | |
| Submitter | Unknown Unknown | |
| Submitter affiliation or code | ||
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
|
|
| Production method | in-house breeding | |
| Origin (In-house) | Organization | Osaka University |
| Organization code | Unknown | |
| Developer | Kanji Yoshida | |
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Il6st (synonim:gp130) |
| Gene name | interleukin 6 signal transducer |
| Allele symbol | Il6sttm1 |
| Allele name | targeted mutation 1 |
| MGI | |
| Chromosome | 13 (67.0) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| OMIM | OMIM ID: 600694 Human Gene Symbol: IL6ST, |
| p-370 | CCCCAACCTTAACATTATGGAGGTAG |
| P-neo | CCGACTGCATCTGCGTGTTCGAATT |
| Author | KANJI YOSHIDA, TETSUYA TAGA, MIKIYOSHI SAITO, SACHIKO SUEMATSU, ATSUSHI KUMANOGOH, TAKASHI TANAKA, HIROSHI FUJIWARA, MORITOSHI HIRATA, TAMOTSU YAMAGAMI, TATSUTOSHI NAKAHATA, TOMOKO HIRABAYASHI, YOSHIHIRO YONEDA, KAZUHIKO TANAKA, WEI-ZHONG WANG, CHISATO MO |
| Title | Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders (myocardial development/hematopoiesis) |
| Journal | Medical Science |
| Volume | 93 |
| Page | 407-411 |
| Year | 1996 |
| PMID | 12093905 |
| Disease name, Applicable field | Neurobiology, Development |