CARD R-BASE



Mouse strain


Strain information

CARD ID 1822
Type of strain Targeted mutant.
Strain name B6.Cg-Bcl9ltm1Taki
Internal Code B9L KO
Submitter Akiyama Tetsu
Submitter affiliation or code Laboratory of Molecular and Genetic Information Institute for Molecular and Cellular Biosciences The University of Tokyo
Stock Type
Material Transfer Conditions No condition
Production method in-house breeding
Origin (In-house) Organization Institute of Molecular and Cellular Biosciences, The University of Tokyo
Organization code Taki
Developer Tetsu Akiyama
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Bcl9l
Gene name B-cell CLL/lymphoma 9-like
Allele symbol Bcl9ltm1
Allele name B-cell CLL/lymphoma 9-like; targeted mutation 1, Tetsu Akiyama
MGI MGI:1933114,
Chromosome 9 (24.84) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation
OMIM

PCR Primer 1
Bcl9l forward CCAGCACCAGAATGTGAACCAAGGACCCAC
Bcl9l reverse GCACCATGAGGCACAGCATCAATGGGCACTC
PCR Primer 2
Neo forward TCGTGCTTTACGGTATCGCCGCTCCCGATT
Bcl9l reverse GCACCATGAGGCACAGCATCAATGGGCACTC
PCR Primer 3
Bcl9ltypeFW2 TGTCCCCTCGGGGCCACTGCC
LacZtypeRV AGGGCGATCGGTGCGGGCCT


References

Author Ken Matsuura, Takafumi Jigami, Kenzui Taniue, Yasuyuki Morishita, Shungo Adachi, Takao Senda, Aya Nonaka, Hiroyuki Aburatani, Tsutomu Nakamura and Tetsu Akiyama
Title Identification of a link between Wnt/beta-catenin signaling and the cell fusion pathway
Journal Nature Communications
Volume 2
Page 548
Year 2011
PMID
Author Shungo Adachi, Takafumi Jigami, Toshio Yasui, Tetsuhiro Nakano, Susumu Ohwada, Yoshihiro Omori, Sumio Sugano, Bisei Ohkawara, Hiroshi Shibuya, Tsutomu Nakamura, Tetsu Akiyama
Title Role of a BCL9-Related Beta-Catenin-Binding Protein, B9L, in Tumorigenesis Induced by Aberrant Activation of Wnt Signaling
Journal Cancer Research
Volume 64
Page 8496-8501
Year 2004
PMID


Disease , Applicable field information

Disease name, Applicable field Development, Cell biology






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