CARD R-BASE



Mouse strain


Strain information

CARD ID 88
Type of strain Targeted mutant.
Strain name C57BL/6-Rag1tm1(GFP)Imku
Internal Code , RAG 1 knock-in mouse
Submitter Nobuo SAKAGUCHI
Submitter affiliation or code Kumamoto University School of Medicine, Department of Immunoloy
Stock Type
Material Transfer Conditions Others
Production method in-house breeding
Origin (In-house) Organization Imku
Organization code Imku
Developer Nobuo Sakaguchi
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol GFP
Gene name Green Fluorescence Protein
Allele symbol
Allele name
MGI
Chromosome
Gene classification Targeted or trapped gene(knockout etc.)
Method Other Homologous
OMIM
Gene symbol Rag1
Gene name Recombination-activating gene 1
Allele symbol
Allele name
MGI MGI:97848,
Chromosome 2 (56.0cM) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Other Homologous
OMIM OMIM ID: 179615 Human Gene Symbol: RAG1,



References

Author Robert C. Rickert, Jurgen Roes and Klaus Rajewsky
Title B Iymphocyte-specific, Cre-mediated mutagenesis in mice
Journal Nucleic Acids Research
Volume 25
Page 1317-1318
Year 1997
PMID 9092650
Author Yousuke Takahama, Kazuhito Ohishi, Yayoi Tokoro, Takehiko Sugawara, Yasuhide Yoshimura, Masaru Okabe, Taroh Kinoshita and Junji Takeda
Title Functional competence of T cells in the absence of glycosylphosphatidylinositol-anchored proteins caused by T cell-specific disruption of the Pig-a gene
Journal Eur. J. Immunol.
Volume 28
Page 2159-2166
Year 1998
PMID 9692885
Author Naomi Kuwata, Hideya Igarashi, Takafumi Ohmura, Shinichi Aizawa, and Nobuo Sakaguchi
Title Cutting Edge: Absence of Expression of RAG1 in Peritoneal B-1 Cells Detected by Knocking into RAG1 Locus with Green Fluorescent Protein Gene
Journal The Journal of Immunology
Volume 163
Page 6355-6359
Year 1999
PMID 10586023
Author Araki, K., Araki, M., Miyazaki, J. & Vassalli, P.
Title Site-Specific Recombination of a Transgene in Fertilized Eggs by Transient Expression of Cre Recombinase
Journal Proc. Natl. Acad. Sci. USA
Volume 92
Page 160-164
Year 1995
PMID 7816809


Disease , Applicable field information

Disease name, Applicable field






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