CARD R-BASE



Mouse strain


Strain information

CARD ID 3376
Type of strain Targeted mutant.
Strain name C3H.Cg-Rab27btm1
Internal Code Rab27b KO マウス
Submitter Katsuhide Okunishi
Submitter affiliation or code Institute for Molecular and Cellular Regulation, Gunma University
Stock Type
Material Transfer Conditions Consent to us
1. Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITORs using the Approval Form.
2. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research.
3. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITORs is requested.
4. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITORs is requested.
5. The RECIPIENT must contact the DEPOSITORs in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Production method in-house breeding
Origin (In-house) Organization Institute for Molecular and Cellular Regulation
Organization code
Developer Hiroshi Gomi, Tetsuro Izumi
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Rab27b
Gene name RAB27B, member RAS oncogene family
Allele symbol Rab27btm1
Allele name RAB27B, member RAS oncogene family; targeted mutation 1,
MGI MGI:1931295,
Chromosome
Gene classification Targeted or trapped gene(knockout etc.)
Method
OMIM

PCR Primer 1
Rab27b/Fow GCATGCAGAGTGAATCAACT
Rab27b/Rev CAAGAGATAGCGTCACTCAAC
NLacZ/Rev TGTGAGCGAGTAACAACCCG


References

Author Hiroshi Gomi, Kenichi Mori, Shigeyoshi Itohara, Tetsuro Izumi
Title Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane
Journal Mol Biol Cell
Volume 18
Page 4377-86
Year 2007
PMID 17761531


Disease , Applicable field information

Disease name, Applicable field Metabolism, Endocrine Disorders, Cell biology, Molecular biology






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