CARD R-BASE



Mouse strain


Strain information

CARD ID 2189
Type of strain Targeted mutant.
Strain name C57BL/6J-Politm1Lgh
Internal Code C57BL/6J-Poliotatm1Gh1
Submitter Sugiura Tetsurou
Submitter affiliation or code -
Stock Type
Material Transfer Conditions Others
Production method in-house breeding
Origin (In-house) Organization Kochi University Scholl of Medicine
Organization code -
Developer Gang-Hong Lee
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Poli
Gene name polymerase (DNA directed), iota
Allele symbol Politm1Lgh
Allele name polymerase (DNA directed), iota, Targeted mutation 1, Gang-Hong Lee
MGI MGI:1347081,
Chromosome 18 (44.48) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation
OMIM

PCR Primer 1
Null L2 5' -GCATGCATTCCTTAGCACAG-3'
Null R2 5' -ACTCACAAGCTGCACAGCAC-3'


References

Author M lguchi, M Osanai, Y Hayashi, F Koentgen and G-H Lee
Title The error-prone DNA polymerase i provides quantitative resistance to lung tumorigenesis and mutagenesis in mice
Journal Oncogene
Volume
Page 1-6
Year 2013
PMID


Disease , Applicable field information

Disease name, Applicable field cancer






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