CARD R-BASE



Mouse strain


Strain information

CARD ID 1973
Type of strain Targeted mutant.
Strain name C57BL/6-Tbxa2r tm1Sna
Internal Code TPKO
Submitter Narumiya Shuh
Submitter affiliation or code Innovation Center for Immunoregulation Technologies and Drugs, Kyoto University Graduate School of Medicine
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Kyoto University Graduate School of Medicine, Department of pharmacology
Organization code Sna
Developer Shuh Narumiya
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Tbxa2r
Gene name thromboxane A2 receptor
Allele symbol Tbxa2rtm1Sna
Allele name thromboxane A2 receptor, targeted mutation 1, Shuh Narumiya, Kyoto University
MGI MGI:98496,
Chromosome 10 (39.72) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation
OMIM

PCR Primer 1
ML136 AAGCTTGGGTTTCAGGGACCTG
ML139 ACTTTGTTGCAGACACCACCTGTC
PCR Primer 2
ML136 AAGCTTGGGTTTCAGGGACCTG
Neo2 TGATATTGCTGAAGAGCTTGGCGGCGAA


References

Author Kabashima K et al.
Title Nat Immunol
Journal Thromboxane A2 modulates interaction of dendritic cells and T cells and regulates acquired immunity
Volume 4
Page 694-701
Year 2003
PMID


Disease , Applicable field information

Disease name, Applicable field






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