| CARD ID | 2916 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6D2-Zp2em1Osb | |
| Internal Code | Zp2 em1 KO | |
| Submitter | Ikawa Masahito | |
| Submitter affiliation or code | Animal Resource Center for Infectious Diseases Research Institute for Microbial Diseases Osaka University | |
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again. |
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| Production method | in-house breeding | |
| Origin (In-house) | Organization | |
| Organization code | ||
| Developer | ||
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Zp2 |
| Gene name | zona pellucida glycoprotein 2 |
| Allele symbol | Zp2em1Osb |
| Allele name | zona pellucida glycoprotein 2; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University |
| MGI | MGI:99214, |
| Chromosome | |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| OMIM |
| Author | Shunsuke Nishio, Chihiro EmCell .ori, Benjamin Wiseman, Dirk Fahrenkamp, Elisa Dioguardi, Sara Zamora-Caballero, Marcel Bokhove, Ling Han, Alena Stsiapanava, Blanca Algarra, Yonggang Lu, Mayo Kodani, Rachel E Bainbridge, Kayla M Komondor, Anne E Carlson, Michael Landreh, Daniele de Sanctis, Shigeki Yasumasu, Masahito Ikawa, Luca Jovine |
| Title | ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat |
| Journal | Cell |
| Volume | 14;187(6) |
| Page | 1440-1459 |
| Year | 2024 |
| PMID | 38490181 |
| Disease name, Applicable field |