| CARD ID | 534 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6.129-Chrm2tm1 | |
| Internal Code | 2NJ, B6.129-Chrm2tm1 | |
| Submitter | Unknown Unknown | |
| Submitter affiliation or code | ||
| Stock Type | ||
| Material Transfer Conditions |
Others
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| Production method | in-house breeding | |
| Origin (In-house) | Organization | Graduate Sch. Pharm. Sci., Univ. Tokyo |
| Organization code | ||
| Developer | MATSUI Minoru | |
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Chrm2 |
| Gene name | cholinergic receptor, muscarinic 2, cardiac |
| Allele symbol | Chrm2tm1 |
| Allele name | targeted mutation 1 |
| MGI | MGI:88397, |
| Chromosome | 6 (syntenic) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| GO | Gene Ontology |
| OMIM | OMIM ID: 118493 Human Gene Symbol: CHRM2, |
| Author | Hiroshi Karasawa, Makoto M. Taketo, Minoru Matsui |
| Title | Loss of anti-cataleptic effect of scopolamine in mice lacking muscarinic acetylcholine receptor subtype 4 |
| Journal | European Journal of Pharmacology |
| Volume | 468 |
| Page | 15-19 |
| Year | 2003 |
| PMID | 12729838 |
| Author | Minoru Matsui, Daisuke Motomura, Hiroshi Karasawa, Toru Fujikawa, Jian Jiang, Yuriko Komiya, Shin-ichi Takahashi, and Makoto M. Taketo |
| Title | Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype |
| Journal | PNAS |
| Volume | 97 |
| Page | 9579-9584 |
| Year | 2000 |
| PMID | 10944224 |
| Author | Minoru Matsui, Daisuke Motomura, Toru Fujikawa, Jian Jiang, Shin-ichi Takahashi, Toshiya Manabe, and Makoto M. Taketo |
| Title | Mice Lacking M2 and M3 Muscarinic Acetylcholine Receptors Are Devoid of Cholinergic Smooth Muscle Contractions But Still Viable |
| Journal | The Journal of Neuroscience |
| Volume | 22 |
| Page | 10627-10632 |
| Year | 2002 |
| PMID | 12486155 |
| Author | Takako Ohno-Shosaku, Minoru Matsui, Yuko Fukudome, Jumpei Shosaku, Hiroshi Tsubokawa, Makoto M. Taketo, Toshiya Manabe and Masanobu Kano |
| Title | Postsynaptic M1 and M3 receptors are responsible for the muscarinic enhancement of retrograde endocannabinoid signalling in the hippocampus |
| Journal | European Journal of Neuroscience |
| Volume | 18 |
| Page | 109-116 |
| Year | 2003 |
| PMID | 12859343 |
| Author | Takeshi Nakamura, Minoru Matsui, Keiko Uchida, Akira Futatsugi, Shinji Kusakawa, Nagisa Matsumoto, Kyoko Nakamura, Toshiya Manabe, Makoto M. Taketo and Katsuhiko Mikoshiba |
| Title | M3 muscarinic acetylcholine receptor plays a critical role in parasympathetic control of salivation in mice |
| Journal | J Physiol |
| Volume | 558 |
| Page | 561-575 |
| Year | 2004 |
| PMID | 15146045 |
| Disease name, Applicable field | Metabolism, Neurobiology, cancer, Immunology, Development, Anatomy, Physiology |