CARD R-BASE



Mouse strain


Strain information

CARD ID 528
Type of strain Targeted mutant.
Strain name B6;129-Rph3altm1Kusm
Internal Code NOC2 kncokout mouse, B6;129-Rph3altm1Kusm
Submitter Unknown Unknown
Submitter affiliation or code
Stock Type
Material Transfer Conditions Others
Production method in-house breeding
Origin (In-house) Organization Div Cell & Mol Med, Kobe Univ Grad Sch Med
Organization code Kusm
Developer Susumu Seino
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Rph3al (Synonym:Noc2)
Gene name rabphilin 3A-like (without C2 domains)
Allele symbol Rph3altm1Kusm
Allele name targeted mutation 1, Division of Cellular and Molecular Medicine, Kobe University School of Medicine
MGI
Chromosome 11 ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation
OMIM OMIM ID: 604881 Human Gene Symbol: RPH3AL,

PCR Primer 1
Excm3 version Neo Rev 5'-AAg CAT gTC CTA CAT gAT gt-3'
Excm3 version Fwd 5'-TCTATC gCC TTC TTg ACg AgT-3'


References

Author Masanari Matsumoto, Takashi Miki, Tadao Shibasaki, Miho Kawaguchi, Hidehiro Shinozaki, Junko Nio, Atsunori Saraya, Haruhiko Koseki, Masaru Miyazaki, Toshihiko Iwanaga, and Susumu Seino
Title Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells
Journal PNAS
Volume 101
Page 8313-8318
Year 2004
PMID 15159548


Disease , Applicable field information

Disease name, Applicable field Metabolism, Anatomy, Physiology






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