CARD R-BASE



Mouse strain


Strain information

CARD ID 681
Type of strain Transgenic.
Strain name C57BL/6J-Tg(CMV-SMURF2)21
Internal Code CMV -FLAG-Smurf2-Tg-line21,CMV-F-Smurf2(21)
Submitter Unknown Unknown
Submitter affiliation or code
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Dept. of Biochem., The JFCR Cancer Institute
Organization code
Developer Takeshi IMAMURA
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol SMURF2
Gene name Smad ubiquitin reguratory factor2
Allele symbol
Allele name
MGI
Chromosome Unknown ,
Gene classification Gene to express(transgenic)
Method MicroInjection
OMIM OMIM ID: 605532 Human Gene Symbol: SMURF2,

PCR Primer 1
Tg-FLAG-SN 5'-ATggACTACAAggACgATgATgACAAgg-3'
Tg-Smurf2-AS 5'-gTTTAgATACTggATTCTTCCAgAggCg-3'


References

Author Mitsuru Horiki, Takeshi Imamura, Mina Okamoto, Makoto Hayashi, Junko Murai, Akira Myoui, Takahiro Ochi, Kohei Miyazono, Hideki Yoshikawa, and Noriyuki Tsumaki
Title Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia
Journal Cell Biology
Volume 165
Page 433-445
Year 2004
PMID


Disease , Applicable field information

Disease name, Applicable field Development, cancer






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