CARD ID | 400 | |
Type of strain | Transgenic. | |
Strain name | C57BL/6-Tg(EF1-MCL1)12Jko | |
Internal Code | EA-Tg E12, C57BL/6-Tg(EF1α-MCL1)12Jko | |
Submitter | Unknown Unknown | |
Submitter affiliation or code | ||
Stock Type | ||
Material Transfer Conditions |
Consent to us
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Production method | in-house breeding | |
Origin (In-house) | Organization | Keio University |
Organization code | Jko | |
Developer | Akihiro Umezawa | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | MCL1(Synonym:EAT) |
Gene name | Myeloid cell leukemia sequence 1 (BCL2-related) (Human) |
Allele symbol | |
Allele name | |
MGI | |
Chromosome | Unknown , |
Gene classification | Gene to express(transgenic) |
Method | MicroInjection |
OMIM | OMIM ID: 159552 Human Gene Symbol: MCL1, |
primerA | 5'(tga aga tgg tag ggt gga aag ac)3' |
primerB | 5'(cac tgg cat tct tag tgc ttc tc)3' |
Author | Kenichi Matsushita, Hajime Okita, Atsushi Suzuki, Kouji Shimoda, Mariko Fukuma, Taketo Yamada, Fumihiko Urano, Takahiro Honda, Makoto Sano, Shiro Iwanaga, Satoshi Ogawa, Jun-ichi Hata, Akihiro Umezawa |
Title | Islet cell hyperplasia in transgenic mice overexpressing EAT/mcl-1, a bcl-2 related gene |
Journal | Molecular and Cellular Endocrinology |
Volume | 203 |
Page | 105-116 |
Year | 2003 |
PMID | 12782407 |
Disease name, Applicable field | cancer, Metabolism |