Mouse strain

Strain information

CARD ID 2821
Type of strain Targeted mutant.
Strain name B6D2-Fam221bem1Osb
Internal Code Fam221b KO
Submitter Ikawa Masahito
Submitter affiliation or code Animal Resource Center for Infectious Diseases Research Institute for Microbial Diseases Osaka University
Stock Type
Material Transfer Conditions Others
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again.
Production method in-house breeding
Origin (In-house) Organization
Organization code
Origin (From other organizations) Organization
Organization code
Year introduced
Introduced Generation

Gene information

Gene symbol Fam221b
Gene name Family with sequence similarity 221, member B
Allele symbol Fam221bem1Osb
Allele name Family with sequence similarity 221, member B, endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI MGI:2441678,
Chromosome 4 (23.05) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation


Author Lu Y,Oura S,Matsumura T,Oji A, Sakurai N,Fujihara Y,Shimada K,Miyata H,Tobita T,Noda T,Castaneda JM,Kiyozumi D,Zhang Q,Larasati T,Young SAM,Kodani M,Huddleston CA,Robertson MJ,Coarfa C,Isotani A,Aitken RJ,Okabe M,Matzuk MM,Garcia TX,Ikawa M.
Title CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice.
Journal Biology of Reproduction
Year 2019 Jun 14

Disease , Applicable field information

Disease name, Applicable field

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