CARD R-BASE



Mouse strain


Strain information

CARD ID 2288
Type of strain Targeted mutant.
Strain name B6;129S-Acat1tm1Ishi
Internal Code ACAT1KO
Submitter ISHIBASHI SHUN
Submitter affiliation or code Jichi Medical University
Stock Type
Material Transfer Conditions Others
Production method in-house breeding
Origin (In-house) Organization
Organization code Ishi
Developer Shun Ishibashi
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Acat1SOAT1
Gene name acetyl-Coenzyme A acetyltransferase 1
Allele symbol Acat1tm1Ishi
Allele name acetyl-Coenzyme A acetyltransferase 1, targeted mutation 1, Shun Ishibashi, Jichi Medical University
MGI MGI:87870,
Chromosome 9 (29.12) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method
OMIM

PCR Primer 1
HY30 5'-TCT TGT AAG CTG CTT GTA AGA GTG CC-3'
HY31 5'-AGC TAG TAA GAA CAG TTC CCT TTC CC-3'
SI-75 5'-GAT TGG GAA GAC AAT AGC AGG CAT GC-3'


References

Author Hiroaki Yagyu
Title Absence of ACAT-1 Attenuates Atherosclerosis but Causes Dry Eye and Cutaneous Xanthomatosis in Mice with Congenital Hyperlipidemia
Journal JBC
Volume 275 (28)
Page 21324-21330
Year 2000
PMID


Disease , Applicable field information

Disease name, Applicable field






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