CARD R-BASE



Mouse strain


Strain information

CARD ID 2971
Type of strain Targeted mutant.
Strain name B6D2-Dnah8em1Osb
Internal Code Dnah8 KO
Submitter Ikawa Masahito
Submitter affiliation or code Animal Resource Center for Infectious Diseases Research Institute for Microbial Diseases Osaka University
Stock Type
Material Transfer Conditions Consent to us
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again.
Production method in-house breeding
Origin (In-house) Organization
Organization code
Developer
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Dnah8
Gene name dynein, axonemal, heavy chain 8
Allele symbol Dnah8em1Osb
Allele name dynein, axonemal, heavy chain 8; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI MGI:107714,
Chromosome 17 (15.71) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation
OMIM



References

Author Chunyu Liu , Haruhiko Miyata , Yang Gao , Yanwei Sha , Shuyan Tang , Zoulan Xu , Marjorie Whitfield , Catherine Patrat , Huan Wu , Emmanuel Dulioust , Shixiong Tian , Keisuke Shimada , Jiangshan Cong , Taichi Noda , Hang Li , Akane Morohoshi , Caroline Cazin , Zine-Eddine Kherraf , Christophe Arnoult , Li Jin , Xiaojin He , Pierre F Ray , Yunxia Cao , Aminata Touré , Feng Zhang , Masahito Ikawa
Title Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility
Journal Am J Hum Genet .
Volume 107(2)
Page 330-341
Year 2020
PMID


Disease , Applicable field information

Disease name, Applicable field






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