Mouse strain

Strain information

CARD ID 2598
Type of strain Targeted mutant.
Strain name B6D2-Tmprss12em1Osb
Internal Code Tmprss12 KO
Submitter Ikawa Masahito
Submitter affiliation or code Animal Resource Center for Infectious Diseases Research Institute for Microbial Diseases Osaka University
Stock Type
Material Transfer Conditions Others
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again.
Production method in-house breeding
Origin (In-house) Organization
Organization code
Origin (From other organizations) Organization
Organization code
Year introduced
Introduced Generation

Gene information

Gene symbol Tmprss12
Gene name transmembrane (C-terminal) protease, serine 12
Allele symbol Tmprss12em1Osb
Allele name transmembrane (C-terminal) protease, serine 12; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI MGI:1922252,
Chromosome 15 (56.24) ,
Gene classification Targeted or trapped gene(knockout etc.)


Author Tamara Larasati, Taichi Noda, Yoshitaka Fujihara, Keisuke Shimada, Tomohiro Tobita, Zhifeng Yu, Martin M. Matzuk, and Masahito Ikawa.
Title Tmprss12 is required for sperm motility and uterotubal junction migration in mice
Journal Biology of Reproduction
Volume ioaa060
Year 25 April 2020

Disease , Applicable field information

Disease name, Applicable field

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