CARD R-BASE



Mouse strain


Strain information

CARD ID 1524
Type of strain Transgenic.
Strain name BKS.NOD-Tg(hIns-TRX)90Miya
Internal Code Ins-TRX mouse
Submitter Miyazaki Jun-ichi
Submitter affiliation or code Division of Stem Cell Regulation Research,Osaka University Graduate School of Medicine
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Osaka University Graduate School of Medicine
Organization code Miya
Developer Jun-ichi Miyazaki
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol TRX
Gene name Thioredoxin
Allele symbol Tg(hIns-TRX)90Miya
Allele name transgene insertion 90 Jun-ichi Miyazaki
MGI
Chromosome
Gene classification Gene to express(transgenic)
Method MicroInjection
OMIM

PCR Primer 1
BG-S0 5'-gCtggTTATTgTgCTgTCTC-3'
hTRX-A1 5'-TCATCCACATCTACTTCAAggA-3'


References

Author Mizuo Hotta, Fumi Tashiro, Hiroshi Ikegami, Hitoshi Niwa, Toshio Ogihara, Junji Yodoi, and Jun-ichi Miyazaki
Title Pancreatic beta Cell–specific Expression of Thioredoxin, an Antioxidative and Antiapoptotic Protein, Prevents Autoimmune and Streptozotocin-induced Diabetes
Journal J.Exp.Med
Volume 188
Page 1445-1451
Year 1998
PMID
Author Mayu Yamamoto, Eiji Yamato, Toyoda Shu-Ichi, Fumi Tashiro, Hiroshi Ikegami, Junji Yodoi, Jun-Ichi Miyazaki
Title Transgenic Expression of Antioxidant Protein Thioredoxin in Pancreatic beta Cells Prevents Progression of Type 2 Diabetes Mellitus
Journal Antioxidants & Redox Signaling
Volume 10
Page 43-50
Year 2008
PMID


Disease , Applicable field information

Disease name, Applicable field Metabolism






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