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CARD Mouse Bank


Mouse strain


Strain information

CARD ID 139
Type of strain Transgenic., Targeted mutant.
Strain name STOCK-Rag2tm1WumTg(Tcra)Wum
Internal Code (B6 x BALB/c x 129)Rag2tm1-TgN(TCR alpha)
Submitter Shigeo Koyasu
Submitter affiliation or code RIKEN
Stock Type
Material Transfer Conditions Consent to us
Production method From other organizations
Origin (In-house) Organization Wum : Washington Univ Sch Med
Organization code Wum
Developer K. M. Murphy
Origin (From other organizations) Organization Harvard Medical School
Organization code Wum
Developer
Year introduced 1994
Introduced Generation
Remarks


Gene information

Gene symbol Tcra
Gene name T-cell receptor alpha chain
Allele symbol
Allele name
MGI MGI:98553,
Chromosome
Gene classification Gene to express(transgenic)
Method Other Homologous,Nonhomologous
GO Gene Ontology
OMIM
Gene symbol Rag2
Gene name Recombination-activating gene 2
Allele symbol
Allele name
MGI MGI:98553,
Chromosome 2 (56.0cM) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Other Homologous,Nonhomologous
GO Gene Ontology
OMIM



References

Author Shigeo Koyasu, Linda K. Clayton, Adam Lerner, Hans Heiken, Alysia Parkes and Ellis L. Reinherz
Title Pre-TCR signaling components trigger transcriptional activation of a rearranged TCRα gene locus and silencing of the pre-TCRα locus: implications for intrathymic differentiation
Journal International Immunology
Volume 9
Page 1475-1480
Year 1997
PMID 9352352


Disease , Applicable field information

Disease name, Applicable field






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