CARD R-BASE



Mouse strain


Strain information

CARD ID 2348
Type of strain Targeted mutant.
Strain name B6.129S6-Gcgtm1Yhys
Internal Code Gcg-GFP
Submitter Kume Shoen
Submitter affiliation or code -
Stock Type
Material Transfer Conditions Consent to us
Production method From other organizations
Origin (In-house) Organization
Organization code
Developer
Origin (From other organizations) Organization Nagoya University
Organization code
Developer Yoshitaka Hayashi
Year introduced 2014 / 8
Introduced Generation
Remarks


Gene information

Gene symbol Gcg
Gene name glucagon
Allele symbol Gcgtm1Yhys
Allele name glucagon; targeted mutation 1, Yoshitaka Hayashi
MGI MGI:95674,
Chromosome 2 (35.85) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method MicroInjection
OMIM

PCR Primer 1
Tm1Yhys Common Fw tgagctcatttggactgcctgc
Tm1Yhys WT rev GGGATATCAATGTAATAACCACAAACGGTA
Tm1Yhys NI rev ATGGTGCGCTCCTGGACGTAG


References

Author Fukami A, Seino Y, Ozaki N, Yamamoto M, Sugiyama C, Sakamoto-Miura E, Himeno T, Takagishi Y, Tsunekawa S, Ali S, Drucker DJ, Murata Y, Seino Y, Oiso Y, Hayashi Y.
Title Ectopic Expression of GIP in Pancreatic beta-Cells Maintains Enhanced Insulin Secretion in Mice With Complete Absence of Proglucagon-Derived Peptides.
Journal Diabetes
Volume 62(2)
Page 510-8
Year 2013
PMID


Disease , Applicable field information

Disease name, Applicable field Development, Diabetes






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