CARD ID | 1058 | |
Type of strain | Targeted mutant. | |
Strain name | B6;129-Gtrgeo22tm1(Rosa26 Stop NICD2)99Imeg | |
Internal Code | Rosa26 Stop NICD2 #99 | |
Submitter | Nishinakamura Ryuichi | |
Submitter affiliation or code | Department of Kidney Development, Institute of Molecular Embryology and Genetics Kumamoto University | |
Stock Type | ||
Material Transfer Conditions |
Consent to us
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|
Production method | in-house breeding | |
Origin (In-house) | Organization | Institute of Molecular Embryology and Genetics, Kumamoto University |
Organization code | Imeg | |
Developer | Ryuichi Nishinakamura | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks | NICD2: intracellular domain of Notch2 |
Gene symbol | Gtrgeo22 |
Gene name | gene trap ROSA b-geo 22 |
Allele symbol | Gtrgeo22tm1(Rosa26 Stop NICD2)99Imeg |
Allele name | targeted mutation 1, Institute of Molecular Embryology and Genetics |
MGI | |
Chromosome | 10 (43.0) , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | Electroporation |
OMIM |
Neo | Forward:AAGGGACTGGCTGCTATTGG, Reverse: ATATCACGGGTAGCCAACGC |
Rosa wild-type | Forward: GAGTTCTCTGCTGCCTCCTG, Reverse: CCGACAAAACCGAAAATCTG |
Author | Fujimura S, Jiang Q, Kobayashi C, and Nishinakamura R |
Title | Notch2 activation in the embryonic kidney depletes nephron progenitors |
Journal | J. Am. Soc. Nephrol |
Volume | 21(5) |
Page | 803-810 |
Year | 2010 |
PMID |
Disease name, Applicable field | Development |