CARD R-BASE



Mouse strain


Strain information

CARD ID 340
Type of strain Transgenic.
Strain name B6;C3-Tg(Myh-SCN5A)
Internal Code hH1 mouse (control mouse), B5C3F1-hH1mouse, B6;C3-Tg(Myh-SCN5A)
Submitter Unknown Unknown
Submitter affiliation or code
Stock Type
Material Transfer Conditions Consent to us
Production method From other organizations
Origin (In-house) Organization
Organization code
Developer
Origin (From other organizations) Organization Gouzo Tsujimoto
Organization code
Developer National Center for child Health and Development
Year introduced 1999
Introduced Generation F2
Remarks


Gene information

Gene symbol SCN5A
Gene name sodium channel, voltage-gated, type V, alpha (long QT syndrome 3) (Human)
Allele symbol
Allele name
MGI MGI:98251,
Chromosome Unknown ,
Gene classification Gene to express(transgenic)
Method MicroInjection
OMIM OMIM ID: 600163 Human Gene Symbol: SCN5A,

PCR Primer 1
primerA 5'(GAAGA,AGCTG,GGCTC,CAAG)3'
primerB 5'(GTTGG,CGAAG,GTCTG,GAAGT)3'


References

Author Qiuyun Chen, Glenn E. Kirsch, Danmei Zhang, Ramon Brugada, Josep Brugada, Pedro Brugada, Domenico Potenza, Angel Moya, Martin Borggrefe, Gunter Breithardt, Rocio Ortiz-Lopez, Zhiqing Wang, Charles Antzelevitch, Richard E. O'Brien, Eric Schulze-Bahr, Mark
Title Genetic basis and molecular mechanism for idiopathic ventricular fibrillation
Journal NATURE
Volume 392
Page 293-296
Year 1998
PMID 9521325
Author Naomasa Makita, MD, PhD; Nobumasa Shirai, MD; Dao W. Wang, MD; Koji Sasaki, MD; Alfred L. George, Jr, MD; Morio Kanno, MD, PhD; Akira Kitabatake, MD, PhD
Title Cardiac Na+ Channel Dysfunction in Brugada Syndrome Is Aggravated by β1-Subunit
Journal Circulation
Volume 101
Page 54-60
Year 2000
PMID 10618304


Disease , Applicable field information

Disease name, Applicable field Physiology






Copyright @ 2021 Kumamoto University. All rights reserved.