| CARD ID | 340 | |
| Type of strain | Transgenic. | |
| Strain name | B6;C3-Tg(Myh-SCN5A) | |
| Internal Code | hH1 mouse (control mouse), B5C3F1-hH1mouse, B6;C3-Tg(Myh-SCN5A) | |
| Submitter | Unknown Unknown | |
| Submitter affiliation or code | ||
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
|
|
| Production method | From other organizations | |
| Origin (In-house) | Organization | |
| Organization code | ||
| Developer | ||
| Origin (From other organizations) | Organization | Gouzo Tsujimoto |
| Organization code | ||
| Developer | National Center for child Health and Development | |
| Year introduced | 1999 | |
| Introduced Generation | F2 | |
| Remarks | ||
| Gene symbol | SCN5A |
| Gene name | sodium channel, voltage-gated, type V, alpha (long QT syndrome 3) (Human) |
| Allele symbol | |
| Allele name | |
| MGI | MGI:98251, |
| Chromosome | Unknown , |
| Gene classification | Gene to express(transgenic) |
| Method | MicroInjection |
| OMIM | OMIM ID: 600163 Human Gene Symbol: SCN5A, |
| primerA | 5'(GAAGA,AGCTG,GGCTC,CAAG)3' |
| primerB | 5'(GTTGG,CGAAG,GTCTG,GAAGT)3' |
| Author | Qiuyun Chen, Glenn E. Kirsch, Danmei Zhang, Ramon Brugada, Josep Brugada, Pedro Brugada, Domenico Potenza, Angel Moya, Martin Borggrefe, Gunter Breithardt, Rocio Ortiz-Lopez, Zhiqing Wang, Charles Antzelevitch, Richard E. O'Brien, Eric Schulze-Bahr, Mark |
| Title | Genetic basis and molecular mechanism for idiopathic ventricular fibrillation |
| Journal | NATURE |
| Volume | 392 |
| Page | 293-296 |
| Year | 1998 |
| PMID | 9521325 |
| Author | Naomasa Makita, MD, PhD; Nobumasa Shirai, MD; Dao W. Wang, MD; Koji Sasaki, MD; Alfred L. George, Jr, MD; Morio Kanno, MD, PhD; Akira Kitabatake, MD, PhD |
| Title | Cardiac Na+ Channel Dysfunction in Brugada Syndrome Is Aggravated by β1-Subunit |
| Journal | Circulation |
| Volume | 101 |
| Page | 54-60 |
| Year | 2000 |
| PMID | 10618304 |
| Disease name, Applicable field | Physiology |