| CARD ID | 2062 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6;129-Rab8atm1 Rab8btm1 | |
| Internal Code | rab8a,rab8b double knockout mouse | |
| Submitter | - - | |
| Submitter affiliation or code | - | |
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
|
|
| Production method | in-house breeding | |
| Origin (In-house) | Organization | I.M.C.R., Gunma Univ, |
| Organization code | ||
| Developer | Akihiro Harada | |
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Rab8a |
| Gene name | RAB8A, member RAS oncogene family |
| Allele symbol | Rab8atm1 |
| Allele name | RAB8A, member RAS oncogene family, targeted mutation 1 |
| MGI | MGI:96960, |
| Chromosome | 8 (34.84) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| OMIM |
| Gene symbol | Rab8b |
| Gene name | RAB8B, member RAS oncogene family |
| Allele symbol | Rab8btm1 |
| Allele name | RAB8B, member RAS oncogene family, targeted mutation 1 |
| MGI | MGI:2442982, |
| Chromosome | 9 (36.17) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| OMIM |
| 8bWT-S | GTT GGA CAT CTC TTC ACC TAT GC |
| 8bWT-AS | CAG AAG CCC TTC CTC GTT CCT GG |
| Author | Takashi Sato, Tomohiko Iwano, Masataka Kunii, Shinji Matsuda, Rumiko Mizuguchi, Yongwook Jung, Haruo Hagiwara, Yoshihiro Yoshihara, Michisuke Yuzaki, Reiko Harada and Akihiro Harada |
| Title | Rab8a and Rab8b are essential for multiple apical transport pathways but insufficient for ciliogenesis |
| Journal | Journal of Cell Science |
| Volume | |
| Page | |
| Year | in press |
| PMID |
| Author | Sato T, Mushiake S, Kato Y, Sato K, Sato M, Takeda N, Ozono K, Miki K, Kubo Y, Tsuji A, Harada R, Harada A. |
| Title | The Rab8 GTPase regulates apical protein localization in intestinal cells. |
| Journal | Nature |
| Volume | 448 |
| Page | 366-369 |
| Year | 2007 |
| PMID |
| Disease name, Applicable field | Physiology, Anatomy |