| CARD ID | 1839 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6;129-Tdgtm1 | |
| Internal Code | Tdg kncokout mouse | |
| Submitter | Ono Tetsuya | |
| Submitter affiliation or code | Department of Cell Biology, Tohoku University School of Medicine | |
| Stock Type | ||
| Material Transfer Conditions |
Others
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| Production method | in-house breeding | |
| Origin (In-house) | Organization | |
| Organization code | ||
| Developer | ||
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Tdg |
| Gene name | thymine DNA glycosylase |
| Allele symbol | Tdg |
| Allele name | targeted mutation 1 |
| MGI | |
| Chromosome | 10 (39.72) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | |
| OMIM |
| Tdg (c) | 5' ACATTCCTAACTCGCTTGCTCA 3' |
| Tdg (wt) | 5' CTCTCAACCACTGCCATCTC 3' |
| Tdg (c) | 5' ACATTCCTAACTCGCTTGCTCA 3' |
| Tdg (m) | 5' CAGCCTCTGTTCCACATACACTTC 3' |
| Author | Yusuke Saito, Tetsuya Ono, Naoki Takeda, Takehiko Nohmi, Masayuki Seki, Takemi Enomoto, Tetsuo Noda, Yoshihiko Uehara |
| Title | Embryonic lethality in mismatch-specific thymine DNA glycosylase deficient mice is partially prevented by DOPS, a precursor of noradrenaline |
| Journal | Tohoku J. Exp. Med. |
| Volume | 226 |
| Page | 75-83 |
| Year | 2012 |
| PMID |
| Disease name, Applicable field | Others, Molecular biology |