CARD ID | 1839 | |
Type of strain | Targeted mutant. | |
Strain name | B6;129-Tdgtm1 | |
Internal Code | Tdg kncokout mouse | |
Submitter | Ono Tetsuya | |
Submitter affiliation or code | Department of Cell Biology, Tohoku University School of Medicine | |
Stock Type | ||
Material Transfer Conditions |
Others
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Production method | in-house breeding | |
Origin (In-house) | Organization | |
Organization code | ||
Developer | ||
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Tdg |
Gene name | thymine DNA glycosylase |
Allele symbol | Tdg |
Allele name | targeted mutation 1 |
MGI | |
Chromosome | 10 (39.72) , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | |
OMIM |
Tdg (c) | 5' ACATTCCTAACTCGCTTGCTCA 3' |
Tdg (wt) | 5' CTCTCAACCACTGCCATCTC 3' |
Tdg (c) | 5' ACATTCCTAACTCGCTTGCTCA 3' |
Tdg (m) | 5' CAGCCTCTGTTCCACATACACTTC 3' |
Author | Yusuke Saito, Tetsuya Ono, Naoki Takeda, Takehiko Nohmi, Masayuki Seki, Takemi Enomoto, Tetsuo Noda, Yoshihiko Uehara |
Title | Embryonic lethality in mismatch-specific thymine DNA glycosylase deficient mice is partially prevented by DOPS, a precursor of noradrenaline |
Journal | Tohoku J. Exp. Med. |
Volume | 226 |
Page | 75-83 |
Year | 2012 |
PMID |
Disease name, Applicable field | Others, Molecular biology |