CARD R-BASE



Mouse strain


Strain information

CARD ID 450
Type of strain Targeted mutant.
Strain name B6;129-Runx1tm1(Runx1)
Internal Code AML1WT/WT (wild type AML1 cDNA knock in mouse), B6;129-Runx1tm1(Runx1)
Submitter Unknown Unknown
Submitter affiliation or code
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Kyoto Prefectural University of Medicine
Organization code
Developer OKUDA, Tsukasa
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Runx 1(synonym:Aml1)
Gene name runt-related transcription factor 1
Allele symbol Runx1tm1
Allele name Runx 1, targeted mutation 1
MGI
Chromosome 16 (62.2 cM) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation
OMIM OMIM ID: 151385 Human Gene Symbol: RUNX1,

PCR Primer 1
primerA AML-P3: ctg atg tct gca ttt gtc cct tgg
primerB


References

Author Motohiro Nishimura, Yoko Fukushima-Nakase, Yasuko Fujita, Mitsushige Nakao, Shogo Toda, Nobuo Kitamura, Tatsuo Abe, and Tsukasa Okuda
Title VWRPY motif-dependent and -independent roles of AML1/Runx1 transcription factor in murine hematopoietic development
Journal Blood
Volume 103
Page 562-570
Year 2004
PMID 14504086


Disease , Applicable field information

Disease name, Applicable field Neurobiology, cancer, Immunology, Development






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