CARD ID | 2189 | |
Type of strain | Targeted mutant. | |
Strain name | C57BL/6J-Politm1Lgh | |
Internal Code | C57BL/6J-Poliotatm1Gh1 | |
Submitter | Sugiura Tetsurou | |
Submitter affiliation or code | - | |
Stock Type | ||
Material Transfer Conditions |
Others
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Production method | in-house breeding | |
Origin (In-house) | Organization | Kochi University Scholl of Medicine |
Organization code | - | |
Developer | Gang-Hong Lee | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Poli |
Gene name | polymerase (DNA directed), iota |
Allele symbol | Politm1Lgh |
Allele name | polymerase (DNA directed), iota, Targeted mutation 1, Gang-Hong Lee |
MGI | MGI:1347081, |
Chromosome | 18 (44.48) , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | Electroporation |
OMIM |
Null L2 | 5' -GCATGCATTCCTTAGCACAG-3' |
Null R2 | 5' -ACTCACAAGCTGCACAGCAC-3' |
Author | M lguchi, M Osanai, Y Hayashi, F Koentgen and G-H Lee |
Title | The error-prone DNA polymerase i provides quantitative resistance to lung tumorigenesis and mutagenesis in mice |
Journal | Oncogene |
Volume | |
Page | 1-6 |
Year | 2013 |
PMID |
Disease name, Applicable field | cancer |