CARD R-BASE



Mouse strain


Strain information

CARD ID 2730
Type of strain Insertion mutant.
Strain name C57BL/6-Mbpem1Nn
Internal Code Golli-MBP flox mouse
Submitter Haruko Miyazaki
Submitter affiliation or code Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Doshisha University
Organization code
Developer Nobuyuki Nukina
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Mbp
Gene name Myelin basic protein
Allele symbol Mbpem1Nn
Allele name myelin basic protein; endonuclease-mediated mutation 1, Laboratory for Structural Neuropathology, RIKEN Brain Science Institute,
MGI MGI:96925,
Chromosome
Gene classification Other gene(mutant etc.)
Method Electroporation
OMIM

PCR Primer 1
Golli-flox-FW1 ATCTTTCCCTGAGAGCCCAG
Golli-flox0RV1 ATCCCATGATCCACAGTAGTC
PCR Primer 2
Golli-flox-FW2 TCATGGCCTGGAAGCAAGTG
Golli-flox-RV2 AGTCCAGTGGATCACAGGTG


References

Author Miyazaki H, Nishioka S, Yamanaka T, Abe M, Imamura Y, Miyasaka T, Kakuda N, Oohashi T, Shimogori T, Yamakawa K, Ikawa M, Nukina N.
Title Generation and characterization of cerebellar granule neurons specific knockout mice of Golli-MBP
Journal Transgenic Research
Volume
Page
Year 2024
PMID 38684589


Disease , Applicable field information

Disease name, Applicable field Neurobiology, Cell biology, Laboratory-animal Science, Development, Molecular biology






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