CARD R-BASE



Mouse strain


Strain information

CARD ID 385
Type of strain Transgenic.
Strain name B6;C-Tg(Mt1-RET)242Num
Internal Code B6;C-Tg(Mt1-RFP/RET)242Num
Submitter Kato Masashi
Submitter affiliation or code Nagoya University Graduate School of Medicine Department of Occupational and Environmental Health
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Nagoya University Graduate School of Medicine
Organization code Num
Developer Masashi Kato
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Ret
Gene name Ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)(Human)
Allele symbol
Allele name
MGI MGI:97902,
Chromosome Unknown ,
Gene classification Gene to express(transgenic)
Method MicroInjection
GO Gene Ontology
OMIM OMIM ID: 164761 Human Gene Symbol: RET,

PCR Primer 1
primerA 5'(aaaatgcagtcagatatgga)3'
primerB 5'(actcggggaggcgttc)3'


References

Author Masashi Kato Nakajima Izumi Masahide Takahashi
Title Mouse models for Hirschsprung's disease and Malignant melanoma
Journal Pathology and clinical
Volume 16
Page 1149-1152
Year 1998
PMID
Author Takashi Iwamoto, Masahide Takahashi, Masafumi Ito, Kiyohiro Hamatani, Masaharu Ohbayashi, Worawidh Wajjwalku, Ken-ichi Isobe and Izumi Nakashima
Title Aberrant melanogenesis and melanocytic tumour development in transgenic mice that carry a metallothionein/ret fusion gene
Journal The EMBO Journal
Volume 10
Page 3167-3175
Year 1991
PMID 1915289


Disease , Applicable field information

Disease name, Applicable field cancer, Dermatology






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