CARD ID | 527 | |
Type of strain | Targeted mutant. | |
Strain name | B6.129-Kcnj8tm1Kusm | |
Internal Code | Kir6.1 deficient mouse, B6.129-Kcnj8tm1Kusm | |
Submitter | Unknown Unknown | |
Submitter affiliation or code | ||
Stock Type | ||
Material Transfer Conditions |
Others
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Production method | in-house breeding | |
Origin (In-house) | Organization | Div Cell & Mol Med, Kobe Univ Grad Sch Med |
Organization code | Kusm | |
Developer | Susumu Seino | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Kcnj8 (Synonym:Kir6.1) |
Gene name | potassium inwardly-rectifying channel, subfamily J, member 8 |
Allele symbol | Kcnj8tm1Kusm |
Allele name | targeted mutation 1, Division of Cellular and Molecular Medicine, Kobe University School of Medicine |
MGI | |
Chromosome | 6 (70.0 cM) , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | Electroporation |
OMIM | OMIM ID: 600935 Human Gene Symbol: KCNJ8, |
Kir6.1-KO-3fw | 5'-AAT GGC CGA TCC CAT ATT GG-3' |
Kir6.1-KO-2rc | 5'-CTG AAC TGG TGA TGA GTG CA-3' |
Author | TAKASHI MIKI, MASASHI SUZUKI, TADAO SHIBASAKI, HIROKO UEMURA, TOSHIAKI SATO, KAORI YAMAGUCHI, HARUHIKO KOSEKI, TOSHIHIKO IWANAGA, HARUAKI NAKAYA & SUSUMU SEINO |
Title | Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1 |
Journal | NATURE MEDICINE |
Volume | 8 |
Page | 466-472 |
Year | 2002 |
PMID | 11984590 |
Disease name, Applicable field | Neurobiology, Physiology |