CARD R-BASE



Mouse strain


Strain information

CARD ID 724
Type of strain Targeted mutant.
Strain name B6;129D3-Aqp2tm1(AD)tmd
Internal Code Agp2tm1(AD insert)tmd
Submitter Uchida Shinichi
Submitter affiliation or code
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Tokyo Medical & Dental Univ.
Organization code 不詳
Developer Uchida Shinichi
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Aqp2
Gene name Aquaporin 2
Allele symbol
Allele name
MGI MGI:1096865,
Chromosome 15 ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation
OMIM OMIM ID: 107777 Human Gene Symbol: AQP2,

PCR Primer 1
AQP2Kin Homo Se2 5'-AGA ATC TAC CAG TCC TCA GC
SA comp 5'-CTT GGA TAC CCA GTC CTT CC


References

Author Eisei Sohara, Tatemitsu Rai, Sung-Sen Yang, Keiko Uchida, Kosaku Nitta, Shigeru Horita, Mayuko Ohno, Akihiro Harada, Sei Sasaki, and Shinichi Uchida
Title Pathogenesis and treatment of autosomal-dominant nephrogenic diabetes insipidus caused by an aquaporin 2 mutation
Journal PNAS
Volume 103
Page 14217-14222
Year 2006
PMID


Disease , Applicable field information

Disease name, Applicable field Physiology






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