CARD ID | 1524 | |
Type of strain | Transgenic. | |
Strain name | BKS.NOD-Tg(hIns-TRX)90Miya | |
Internal Code | Ins-TRX mouse | |
Submitter | Miyazaki Jun-ichi | |
Submitter affiliation or code | Division of Stem Cell Regulation Research,Osaka University Graduate School of Medicine | |
Stock Type | ||
Material Transfer Conditions |
Consent to us
|
|
Production method | in-house breeding | |
Origin (In-house) | Organization | Osaka University Graduate School of Medicine |
Organization code | Miya | |
Developer | Jun-ichi Miyazaki | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | TRX |
Gene name | Thioredoxin |
Allele symbol | Tg(hIns-TRX)90Miya |
Allele name | transgene insertion 90 Jun-ichi Miyazaki |
MGI | |
Chromosome | |
Gene classification | Gene to express(transgenic) |
Method | MicroInjection |
OMIM |
BG-S0 | 5'-gCtggTTATTgTgCTgTCTC-3' |
hTRX-A1 | 5'-TCATCCACATCTACTTCAAggA-3' |
Author | Mizuo Hotta, Fumi Tashiro, Hiroshi Ikegami, Hitoshi Niwa, Toshio Ogihara, Junji Yodoi, and Jun-ichi Miyazaki |
Title | Pancreatic beta Cell–specific Expression of Thioredoxin, an Antioxidative and Antiapoptotic Protein, Prevents Autoimmune and Streptozotocin-induced Diabetes |
Journal | J.Exp.Med |
Volume | 188 |
Page | 1445-1451 |
Year | 1998 |
PMID |
Author | Mayu Yamamoto, Eiji Yamato, Toyoda Shu-Ichi, Fumi Tashiro, Hiroshi Ikegami, Junji Yodoi, Jun-Ichi Miyazaki |
Title | Transgenic Expression of Antioxidant Protein Thioredoxin in Pancreatic beta Cells Prevents Progression of Type 2 Diabetes Mellitus |
Journal | Antioxidants & Redox Signaling |
Volume | 10 |
Page | 43-50 |
Year | 2008 |
PMID |
Disease name, Applicable field | Metabolism |