CARD R-BASE



Mouse strain


Strain information

CARD ID 400
Type of strain Transgenic.
Strain name C57BL/6-Tg(EF1-MCL1)12Jko
Internal Code EA-Tg E12, C57BL/6-Tg(EF1α-MCL1)12Jko
Submitter Unknown Unknown
Submitter affiliation or code
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Keio University
Organization code Jko
Developer Akihiro Umezawa
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol MCL1(Synonym:EAT)
Gene name Myeloid cell leukemia sequence 1 (BCL2-related) (Human)
Allele symbol
Allele name
MGI
Chromosome Unknown ,
Gene classification Gene to express(transgenic)
Method MicroInjection
OMIM OMIM ID: 159552 Human Gene Symbol: MCL1,

PCR Primer 1
primerA 5'(tga aga tgg tag ggt gga aag ac)3'
primerB 5'(cac tgg cat tct tag tgc ttc tc)3'


References

Author Kenichi Matsushita, Hajime Okita, Atsushi Suzuki, Kouji Shimoda, Mariko Fukuma, Taketo Yamada, Fumihiko Urano, Takahiro Honda, Makoto Sano, Shiro Iwanaga, Satoshi Ogawa, Jun-ichi Hata, Akihiro Umezawa
Title Islet cell hyperplasia in transgenic mice overexpressing EAT/mcl-1, a bcl-2 related gene
Journal Molecular and Cellular Endocrinology
Volume 203
Page 105-116
Year 2003
PMID 12782407


Disease , Applicable field information

Disease name, Applicable field cancer, Metabolism






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