CARD R-BASE



Mouse strain


Strain information

CARD ID 709
Type of strain Transgenic.
Strain name B6;C3H-Tg(Krt19-Wnt1/K19-Ptgs2/K19-Ptges)
Internal Code B6;C3H-Tg(K19-wnt1/k19-Ptgs2/k19-Ptges), K19-Wnt1/C2mE
Submitter Masanobu Oshima
Submitter affiliation or code Division of Genetics, Cancer Research Institute, Kanazawa University
Stock Type
Material Transfer Conditions Others
Production method in-house breeding
Origin (In-house) Organization Cancer Research Institute, Kanazawa Univ.
Organization code
Developer Hiroko Oshima
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Wnt1, Ptgs2, Ptges
Gene name Wnt1:wingless-related MMTV integration site 1),
Allele symbol
Allele name
MGI
Chromosome Unknown ,
Gene classification Gene to express(transgenic)
Method MicroInjection
OMIM OMIM ID: 164820 Human Gene Symbol: WNT1, OMIM ID: 600262 Human Gene Symbol: PTGS2, OMIM ID: 605172 Human Gene Symbol: PTGES,

PCR Primer 1
Wnt1F,COX-2-F3 CGACCGTGTTCTCTGAGATG,CAAACTCAAGTTTGACCCAG
HA-R,COX-2-R1 CATCATATGGGTAGGCCATGG,CTTTTACAGCTCAGTTGAACG


References

Author Oshima H, Matsunaga A, Fujimura T, Tsukamoto T, Taketo MM, Oshima M.
Title Carcinogenesis in mouse stomach by simultaneous activation of the wnt signaling and prostaglandin e(2) pathway.
Journal Gastroenterology
Volume 131
Page 1086-1095
Year 2006
PMID


Disease , Applicable field information

Disease name, Applicable field cancer






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